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Intermediate Topic 1006 of 1102 Biochemistry, Environment & Industry

Metabolism

All chemical reactions in living organisms, divided into catabolism and anabolism.

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In-depth explanation of Metabolism

Metabolism is the sum of all chemical reactions occurring in a living organism. It is divided into catabolism, in which large molecules are broken down, releasing energy captured as ATP and reduced carriers such as NADH, and anabolism, in which small precursors are assembled into macromolecules using that energy. Metabolic pathways are sequences of enzyme-catalysed steps that are carefully regulated. Feedback inhibition, in which an end product blocks an early enzyme, and hormonal signals adjust the flux through each pathway to meet the cell's needs. The balance between the two halves keeps energy supply matched to demand.

Going deeper: Metabolism

Key ideas: The sum of anabolic (building, uses energy) and catabolic (breaking down, releases energy) reactions. Catabolism of glucose is coupled to making ATP, and anabolism uses ATP and NADPH. Pathways are sequences of enzyme steps with regulation by feedback inhibition and by hormones.

Common mistakes and connections: Mistake: calling a pathway spontaneous overall because ATP is made; individual steps may be uphill and are driven by coupling. Another is thinking anabolic pathways are exact reversals of catabolic ones; they use different enzymes at key steps. Links to thermodynamics free energy and enzymes.

Visualization of Metabolism

Share of resting metabolic energy used by organs. Continuous catabolic pathways supply the ATP for this steady anabolic and transport work. The interactive lesson shows this as a live animation or chart.

Worked example and use case

Glycolysis is a catabolic pathway, while building proteins from amino acids is anabolic.

Frequently asked questions about Metabolism

What is Metabolism?

All chemical reactions in living organisms, divided into catabolism and anabolism.

Is Metabolism a beginner, intermediate or advanced topic?

Metabolism is a intermediate topic in Biochemistry, Environment & Industry. It builds on the vocabulary of beginner topics in this area.

What should I learn before Metabolism?

Study these earlier topics in Biochemistry, Environment & Industry first: Genetic Code, PCR, CRISPR.

What comes after Metabolism?

The next topics in Biochemistry, Environment & Industry are ATP and Glycolysis.

Can I practise Metabolism with quizzes?

Yes. The interactive lesson includes a self-check question on Metabolism, and the Biochemistry, Environment & Industry quiz draws on every topic in this area.

Where Metabolism fits in Biochemistry, Environment & Industry

Metabolism is topic 31 of 127 in Biochemistry, Environment & Industry.

Related topics

Browse all 127 topics in Biochemistry, Environment & Industry